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KMID : 1190719960010010041
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Chonnam Journal of Nursing Science
1996 Volume.1 No. 1 p.41 ~ p.58
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The Influence of Saline and Betadine Solution of Gargle in the Leukemic Patients Receiving Chemotherapy
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Abstract
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Patient receiving chemotherapy experience side-effects such as stomatitis, nausea and vomiting. Stomatitis appears more frequency in the leukemic patients who have bonemarrow depression than those in other cancer patients.
The patients who have stomatitis feel discomfort with pain whenever eat or speak, They also may be serious because the stomatisis could lead them to sepsis or death. So, preventive oral care is strongly required for them.
Since the platelets and WBC level decrease during chemotherapy, leukemic patients need to use gargling solution instead of toothbrushing. Betadine solution which is usually used in clinical setting has so strong odor and displeasing taste that it often causes nausea and vomiting. To the contrary, saline is familiar to the most people and its odor and taste is not bad, and it would be effective in preventing stomatitis as well.
In this context, this study was done to test the effectiveness of saline and betadine solution for leukemic patients, and to suggest which the better gargling solution is.
The subjects, were 40 leukemic patients hospitalized for chemotherapy at the Chonnam university hospital in Kwangju city, were randomly assigned to the saline and betadine solution group according to order of participating study.
Data were gathered from December, 1995 to July, 1996, through checking the patients’ objective oral states by the investigator and self reported subjective oral comfortness before and 4weeks after gargle.
The study design was Quasi-experimental research.
The study instrument(the objective oral state guide and the subjective oral perception guide)was developed by Beck(1979), and was modified by the investigator.
The SAS PC+ program was used to analysis the data with X2-test, t-test, Pearson’s correlation and ANOVA.
The results may be summarized as follows:
The first hypothesis that saline users will have higher objective oral state score than those of betadine solution was supported(t=-2.14, p=.038).
The second hypothesis that Saline users will have higher subjective oral comfortness score than those of betadine solution was rejected.
The third hypothesis that There will be a positive correlation between objective oral state and subjective oral comfortness was supported every week after gargle(Week 1: r=.82, p=.0001; Week 2: r=.90, p=.0001; Week 3: r=.84, p=.0001; Week 4: r=.71, p=.0001).
As the result, saline would be more effective gargling solution than betadine solution for the improvement of oral state in the leukemic patients receiving chemotherapy.
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KEYWORD
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Oral gargle solution, Stomatitis
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